A team of scientists supported by the National Institutes of Health (NIH) has developed a promising blood test that could predict the risk of developing severe respiratory diseases, such as chronic obstructive pulmonary disease (COPD). The test analyzes 32 proteins in the blood to determine an individual’s likelihood of needing…

A pilot study by researchers in the Netherlands has shown the potential of voices recorded on smartphone to detect an impending serious flare up of COPD (chronic obstructive pulmonary disease). COPD is an inclusive term for diseases such as emphysema and chronic bronchitis and is the third leading cause of…

Research from Tongji University in Shanghai shows promising results from a Phase I human study of a cell therapy to treat chronic obstructive pulmonary disease (COPD). A group of 17 patients had notable improvements in breathing, walking distance, and quality of life after receiving the therapy, which is created using…

Chronic Obstructive Pulmonary Disease, or COPD, that results in emphysema or chronic bronchitis is the third leading cause of death worldwide but burden of disease is not shared equally between the sexes. Traditionally, men were more likely to be diagnosed but over the past two decades women have been catching…

A new atlas of the cells in the COPD-afflicted lung has been generated, identifying those cells and pathways that may contribute to the reduced lung function and inflammation characteristic of this disease and that could lead to new therapies. Yale School of Medicine researchers found that genes known to be…

A new preclinical study, published in Science Translational Medicine, led by the Centenary Institute and University of Technology Sydney (UTS) has identified a small RNA molecule called microRNA-21 as a therapeutic target and its inhibition as a potential treatment for COPD. “COPD is the third leading cause of morbidity and…

Chronic obstructive pulmonary disease (COPD) is a group of diseases including emphysema and chronic bronchitis that cause airflow restriction and other breathing-related problems. The Centers for Disease Control (CDC) estimates that COPD, the third highest cause of death around the world, more than 16 million Americans. In the United States,…

The results of research by University of British Columbia scientists suggest that giving up smoking could lessen the chance that an infection with SARS-CoV-2 coronavirus will lead to severe COVID-19 disease. Their studies found that the lung cells of people who are current cigarette smokers, and individuals with chronic obstructive…

Owlstone Medical said today that its Breath Biospsy platform services will be used by AstraZeneca to identify novel biomarkers differentiating between disease phenotypes for asthma and COPD, through a collaboration whose value was not disclosed. AstraZeneca will gain access to Owlstone’s Medical Breath Biopsy services, which include development of classification…

A team of engineers at the California Institute of Technology (Caltech) say they have developed a smart mask that can be worn to monitor a range of medical conditions, including respiratory ailments, asthma, COPD, and post-COVID conditions, and can even show whether a treatment is having the desired effect.  The…

Genetic variation in the EPAS1 gene that influences our ability to store oxygen in the blood may be behind differences in symptoms and outcomes in people with diseases such as chronic obstructive pulmonary disease (COPD). Tatum Simonson, founder and co-director of the Center for Physiological Genomics of Low Oxygen at…

A team of researchers at Vanderbilt University have developed an artificial intelligence (AI) tool that analyzes low-dose CT (LDCT) scans to predict mortality risk of patients. The AI tool uses the scans of patients’ lungs and not only improves risk prediction for death from lung cancer, but also cardiovascular disease…

Chemicals in the breath of patients admitted to hospital can identify which underlying cardiorespiratory disease they are suffering from, research suggests. Exhaled volatile organic compounds were able to distinguish heart failure, asthma, chronic obstructive pulmonary disease (COPD) and pneumonia, according to the study published in Science Translational Medicine. The “breathomics”…

Originally Aired:  June 27, 2022Time: 8:00 am PT, 11:00 am ET, 17:00 CET VIEW NOW In this Learning Lab, we discussed the development of respiratory airway and alveolar organoids derived from human iPSCs and how these are used in modeling respiratory diseases such as cystic fibrosis. Airway organoid models can be used…

By Bob Matthews This article reports the results of a study that follows a multi-year, pragmatic clinical trial in a real world, community based primary care. What started as a quality project evolved to include the development and deployment of Artificial Intelligence (AI) decision support to guide medication choices when…