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Published on June 20, 2024
People resistant to COVID-19 have “never-seen-before” immune responses and possibly high levels of HLA-DQA2. These findings come from researchers at the Wellcome Sanger Institute, University College London (UCL), Imperial College London, the Netherlands Cancer Institute, and their collaborators who used data from a unique “challenge study.” Severe acute respiratory syndrome…
Published on May 22, 2024
The results of two back-to-back randomized double-blind placebo controlled trials has shown that a 100-year-old vaccine originally developed to prevent tuberculosis helps protect people with type 1 diabetes from COVID-19 and other infectious diseases. The research by investigators at the Massachusetts General Hospital (MGH) found that the Bacillus Calmette-Guérin (BCG)…
Published on April 26, 2024
There’s new evidence the COVID-19 mRNA vaccines don’t provide much mucosal immunity, according to a team of French researchers. In a study that included more than 400 patients, there was some mucosal immunity provided by these vaccines, but previously infected people had a greater response. This suggests that new approaches,…
Published on March 20, 2024
SARS-CoV-2, the virus that causes COVID-19, can damage the heart in patients with ARDS (Acute Respiratory Distress Syndrome) without directly infecting heart tissue, a new study has found. These findings suggest it is systemic inflammation that causes this damage. “The research also suggests that suppressing the inflammation through treatments might…
Published on March 5, 2024
A large study led by Kyung Hee University in Seoul shows that infection with SARS-CoV-2 significantly increases the risk of developing autoimmune inflammatory rheumatic disease for up to a year after infection. The research, published in the Annals of Internal Medicine, shows that COVID-19 increased the risk for being diagnosed…
Published on February 21, 2024
A new study has shown that delays in diagnosis of melanoma in Europe due to COVID-19 lockdowns may have contributed to the loss of more than 100,000 life-years and costs that exceed £6 billion, mostly related to loss of productivity. The research, published last week in a new JAMA Network…
Published on February 5, 2024
While researchers have already shown that insomnia was common in patients who have been hospitalized for COVID-19, new findings from a team of scientists in Vietnam found that insomnia was more likely in more than three-quarters of patients who had been diagnosed with a mild infection. The research, reported in…
Published on January 24, 2024
Babies of mothers infected by COVID-19 during pregnancy had three times the risk of respiratory distress compared with unexposed infants, even though the infants themselves were not infected with the virus, in a recent study. The risk of respiratory distress was significantly lower when the mothers were previously vaccinated. According…
Published on December 27, 2023
New research from investigators in the U.K. has shown that markers of brain injury are present many months after COVID-19 infection, despite standard blood testing that is normal. The research, published in Nature Communications, helps provide potential therapy pathways for patients that experience cognitive difficulties after recovering from COVID-19 by…
Published on November 14, 2023
Data from a new study by researchers at Mass General Brigham found that 20% of patients who were treated for severe symptoms had COVID-19 return after being treated with Paxlovid after an initial recovery and negative test result. Only 2% of patients who recovered from COVID-19 and didn’t take Paxlovid…
Published on November 6, 2023
The first mice that display a humanlike form of COVID-19 have been engineered, according to a study published online November 1 in Nature. The authors, from NYU Grossman School of Medicine, created a strain of mice with human genetic material for angiotensin-converting enzyme 2 (ACE2)—a receptor through which SARS-CoV-2 enters…
Published on October 25, 2023
The Global Coalition for Adaptive Research (GCAR) today announced clinical trial results of vitamin C and simvastatin to treat severely ill patients with COVID-19. Simvastatin was shown to have a high probability (96%) of improving outcomes (a combination of survival and length of time patients need support in an intensive…
Published on October 24, 2023
Research led by Weill Cornell Graduate School of Medical Sciences shows that certain species of gut fungi, notably Candida albicans, increase in numbers during serious COVID-19 infection and appear to contribute to the excessive and damaging inflammation seen in these patients. High levels of immunoglobulin G (IgG) antibodies against fungi…
Published on October 16, 2023
Codagenix’s nasal vaccine for COVID-19 delivered positive results in a Phase I trial, according to a presentation at IDWeek’s 2023 annual meeting last week. In tandem, the U.S. awarded almost $20M in funding for nasal COVID-19 development. CastleVax and Codagenix, the only two companies that have delivered Phase I results…
Published on September 29, 2023
SARS-CoV-2 increases the risk of heart attack and stroke by causing fatty plaque in cardiac arteries to become highly inflamed, according to a new study funded by the National Institutes of Health. The findings, published in the journal Nature Cardiovascular Research, may help explain why certain people who get COVID-19 have a greater chance of developing…