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Published on September 11, 2024
A team of scientists supported by the National Institutes of Health (NIH) has developed a promising blood test that could predict the risk of developing severe respiratory diseases, such as chronic obstructive pulmonary disease (COPD). The test analyzes 32 proteins in the blood to determine an individual’s likelihood of needing…
Published on February 12, 2024
Genetic variation in the EPAS1 gene that influences our ability to store oxygen in the blood may be behind differences in symptoms and outcomes in people with diseases such as chronic obstructive pulmonary disease (COPD). Tatum Simonson, founder and co-director of the Center for Physiological Genomics of Low Oxygen at…
Published on August 16, 2022
Chronic diseases cover a wide range of medical conditions from asthma and diabetes to gastrointestinal and heart problems. As the U.S. Center for Disease Control and Prevention (CDC) notes: “Chronic diseases are defined broadly as conditions that last 1 year or more and require ongoing medical attention or limit activities…
Published on July 16, 2021
Researchers at Boston University have discovered a set of signals that control the generation of mucus-secreting goblet cells in the major air passages of the lung that are often found in inflated numbers in lung diseases such as asthma, COPD (Chronic obstructive pulmonary disease), cystic fibrosis, and chronic bronchitis. “By…
Published on September 12, 2023
Research from Tongji University in Shanghai shows promising results from a Phase I human study of a cell therapy to treat chronic obstructive pulmonary disease (COPD). A group of 17 patients had notable improvements in breathing, walking distance, and quality of life after receiving the therapy, which is created using…
Published on May 7, 2021
A 3D lung-on-a-chip model designed by researchers based at Brigham and Women’s Hospital accurately models lung cells and tissue to better understand and help design treatments for conditions such as asthma, chronic obstructive pulmonary disease, influenza and COVID-19. The team currently is studying how COVID-19 viral particles travel through airways…
Published on September 10, 2024
A pilot study by researchers in the Netherlands has shown the potential of voices recorded on smartphone to detect an impending serious flare up of COPD (chronic obstructive pulmonary disease). COPD is an inclusive term for diseases such as emphysema and chronic bronchitis and is the third leading cause of…
Published on May 15, 2024
Researchers based at the University of East Anglia in the U.K. have confirmed that accounting for biological sex when assessing patients for heart failure improves accuracy of diagnosis. The team behind the work, published in the European Heart Journal Open, fine-tuned a method for diagnosing the condition using magnetic resonance…
Published on April 22, 2024
Research led by the University of Pittsburgh suggests that more attention should be paid to people with atrial fibrillation who are younger than 65 years, as they have considerable health issues and a significantly increased risk of dying compared with the general population. “Common knowledge among cardiologists is that, in…
Published on December 19, 2023
Results from a study led by the University of Michigan show that doctors struggle to spot biases in an artificial intelligence (AI) diagnostic model, despite explanations of the model’s methods being available. The model in this study, which is published in JAMA, was designed to help diagnose the cause of…
Published on July 25, 2023
A team of researchers at Vanderbilt University have developed an artificial intelligence (AI) tool that analyzes low-dose CT (LDCT) scans to predict mortality risk of patients. The AI tool uses the scans of patients’ lungs and not only improves risk prediction for death from lung cancer, but also cardiovascular disease…
Published on May 5, 2023
A machine-learning algorithm could offer personalized predictions of life expectancy following lung transplantation, research suggests. The random survival forests (RSF) model had “excellent performance” in predicting both survival overall and at the specific time points of one month and a year, revealed the researchers. It was significantly better than a…
Published on April 19, 2023
A patient questionnaire was used to help design a new software tool to improve management of elderly atrial fibrillation patients with multiple conditions. The investigators defined 22 comorbidities that are common in these patients and then created concise care pathways to guide effective management of certain types of patients. The…
Published on March 28, 2023
Research suggests that people with allergic asthma or eczema are at increased risk for osteoarthritis compared with those without allergies. Osteoarthritis is the most common type of arthritis, impacting approximately one in seven adults in the U.S. “Osteoarthritis is associated with considerable morbidity—it is one of the major contributors to…
Published on February 23, 2023
UK drug discovery company C4X Discovery Holdings Plc. has announced the launch of PatientSeek, its precision medicine platform to identify patients most likely to benefit from a medication based on their genetics. The launch follows its first validation for patient stratification using results from a failed Phase 3 clinical trial…