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Published on December 6, 2023
A new combination of experimental drugs may help treat malignant peripheral nerve sheath tumors (MPNST) with fewer harmful side effects, according to preliminary animal studies led by investigators at Johns Hopkins. The study, published in the journal Molecular Cancer Therapeutics, shows that combining an experimental drug that blocks the metabolism of…
Published on April 3, 2024
Adaptimmune’s pivotal SPEARHEAD-1 trial has shown that the T cell receptor therapy afami-cel effectively targets metastatic synovial sarcoma and myxoid round cell liposarcoma, potentially opening the door for other solid tumors to be treated with T cell therapies. “Synovial sarcoma is a rare cancer with historically limited treatment options and…
Published on September 1, 2021
A blood test could one day offer a highly sensitive and inexpensive approach to detect early cancer in people with neurofibromatosis type 1 (NF1), according to work from researchers at the National Cancer Institute’s (NCI) Center for Cancer Research and Washington University School of Medicine in St. Louis. This blood…
Published on July 27, 2020
Mouse models could help oncologists decide the best treatment course for patients with difficult to treat or metastatic cancers, suggests research from the Catalonian Institute of Oncology and Bellvitge Biomedical Research Institute in Barcelona, Spain. Over approximately 8 months, researchers carried out a study in mice that had been transplanted…