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Published on September 21, 2023
A new review published in The Lancet Neurology by researchers at Mass General Brigham presents findings indicating that cardiovascular disease risk may be increased by traumatic brain injury (TBI). The review presented evidence of the long-term associations between TBI and cardiovascular disease noting that post-injury comorbidities, as well as neuroinflammation,…
Published on July 6, 2023
Depression that develops after traumatic brain injury may be clinically distinct from other depressive disorders, new research by Brigham and Women’s Hospital and collaborators suggests. Brain circuitry differed with this type of depression compared with others, leading researchers to suggest it should be treated as a distinct “TBI affective syndrome.”…
Published on August 22, 2022
Blood tests taken the day of a traumatic brain injury (TBI) can predict which patients are likely to die or survive with severe disability, allowing clinicians to make decisions earlier on possible treatment of TBI, according to a new study. Researchers from Michigan Medicine, the University of California San Francisco,…
Published on July 25, 2022
New biomarkers that distinguish acute from chronic phases of traumatic brain injury (TBI) have been identified by scientists at Arizona State University (ASU). Their work could lead to new therapeutics and diagnostics and also help explain why people who have had TBI are more susceptible to developing neurodegenerative diseases such…
Published on February 27, 2020
Traumatic Brain Injury (TBI) symptoms can be a debilitating injury for patients. A surprising new study from the University of Maryland shows that shutting down the immune system shortly after the initial injury can dramatically lessen future TBI symptoms. The preclinical study suggests that prolonged brain inflammation following injury can…
Published on February 4, 2019
Traumatic brain injury (TBI) has recently become a serious societal concern, as the link between repetitive head traumas and neurodegenerative brain disease has come to light. Yet TBI is signficantly under-reported due to lack of adequate diagnostic tools, sparking great debate about this ‘silent epidemic,’ particularly among professional and youth…
Published on July 16, 2018
Speed is key for medical diagnostics and critical for delivering the appropriate treatment in trauma cases—especially for neurological injuries. Identifying key markers for traumatic brain injury (TBI) is imperative since it is often difficult to evaluate the extent of damage or predict how long the impairment will last or whether…
Published on May 30, 2024
Scientists have inserted a “window” into a patient’s skull to monitor their brain activity in real-time. An individual’s brain activity could be observed outside of the operating room with the help of a custom-made, ultrasound-transparent cranial window implant, which was given to an adult patient undergoing skull reconstruction surgery after…
Published on February 17, 2022
A research team, headed by scientists at the Oslo Sports Trauma Research Center, has identified microRNAs (miRNAs) specific to accidental head impact and repetitive headers in soccer, which could potentially be useful as biomarkers of brain injury. Research lead Stian Bahr Sandmo, PhD, stated, “This is a relatively small sample-size…
Published on January 15, 2021
Research suggests that a build-up of abnormal microRNAs could be behind the increased risk for Alzheimer’s disease seen in patients who experience traumatic brain injury. Results from an animal study carried out at the Walter Reed Army Institute for Research in Maryland showed that micro(mi)RNA changes after brain injury led…
Published on November 12, 2020
The current scale for measuring the severity of a stroke does not correlate well with brain tissue damage. Therefore, markers of tissue damage would allow for better prediction of outcomes and treatment development. Now, a research group has discovered that a biomarker in the blood—a protein known as neurofilament light…
Published on January 26, 2024
Researchers at the City University of Hong Kong (CityU) have found in a mouse study that the application of low-dose ionizing radiation (LDIR) such as X-ray radiation can reduce lesion size and reverse motor deficits in traumatic brain injury (TBI) and ischemic stroke. The method, reported in the journal Brain,…
Published on December 23, 2022
Research by Mark Logue a statistician at the National Center for post-traumatic stress disorder (PTSD) at the VA Boston Health Care System, found a greater percentage of Alzheimer’s disease and related dementias (ADRD) in veterans with PTSD and in those with TBI (traumatic brain injury) who had inherited the ε4…
Published on April 23, 2018
A fall in the street, a tackle on the gridiron, a bomb blast on the battlefield—any of these events can result in a concussion, or mild traumatic brain injury (mTBI). We already know mTBIs are common, but, they may be even more common that we realize, given our lack of…
Published on February 15, 2018
The FDA has approved the first blood test for mild traumatic brain injury (mTBI), an in vitro diagnostic developed by Banyan Biomarkers to identify patients with suspected concussions. Banyan BTI™ is designed to identify two brain-specific protein biomarkers—Ubiquitin Carboxy-terminal Hydrolase-L1 or UCH-L1 and glial fibrilliary acidic protein (GFAP)—that rapidly appear…