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Published on September 21, 2022
Researchers at Friedrich-Alexander-University Erlangen-Nürnberg (FAU), in Germany have successfully cured several patients suffering from severe systemic lupus erythematosus (SLE) using genetically modified immune cells known as CAR-T cells. CAR T cells are immune cells taken from an individual patient and genetically engineered to express proteins known as CAR—chimeric antigen receptors—on…
Published on September 1, 2022
Sponsored content brought to you by Much of healthcare and basic biological research depends on access to data-rich biospecimens. To learn about one of the larger biorepositories involved in multi-omic research, we spoke with Precision for Medicine’s Scientific Director, Anuj Kalsy, and Associate Director of Genomics, Robert Snyder, PhD. [caption…
Published on August 16, 2022
Inside Precision Medicine sits down with Kaitlyn Johnson, PhD, senior data analyst at The Rockefeller Foundation’s Pandemic Prevention Institute (PPI), where her work leverages data analysis and modeling to provide real-time guidance to individuals and decision-makers to prevent and mitigate pandemics. Johnson is an interdisciplinary researcher passionate about developing quantitative…
Published on August 16, 2022
Every virus has its preferred niche — a particular host or demographic it is more inclined to infect and a particular set of strategies and tactics it uses to achieve this. A virus develops a niche over millions of years, all the while adapting and mutating in response to host…
Published on July 22, 2022
A new study has uncovered more details about memory B cell responses to SARS-CoV-2, the virus that causes COVID-19, after recovery from natural infection or post-vaccination. The study, coauthored by David Fear, from King’s College London, is published in Viral Immunology. Many research studies have found that serological SARS-CoV-2-specific IgG antibody…
Published on June 30, 2022
Gene correction and mRNA company ReCode Therapeutics has announced the close of a Series B extension financing round. The series was co-led by new investors, Leaps by Bayer and AyurMaya, and with participation from Amgen Ventures. With the additional $120M in new financing, the company has secured a total of…
Published on June 15, 2022
This year marks the 10-year anniversary of when CRISPR-Cas9 gene editing was first revealed to the world. Much has happened since then, including wide rollout in many sectors, development of CRISPR-based therapeutics and the discovery that the technology can also be used to develop highly accurate and affordable diagnostics. The…
Published on June 15, 2022
The COVID-19 pandemic has driven RNA into the public eye and there is increasing recognition of its importance in medicine. The intense scientific drive and the success of mRNA vaccines during the last two years has also benefitted biotech overall, with an increasing list of new RNA startups entering the…
Published on June 15, 2022
By Norbert Farkas and Hansjörg Schützinger While between 1998 and 2010 only nine approved companion diagnostics were listed by the FDA, 35 new companion diagnostics were approved between 2011 and 2020.1 Novel diagnostics, such as NGS (Next Generation Sequencing), have become more standardized and affordable allowing medicine to move away from…
Published on June 13, 2022
Researchers based at Icahn School of Medicine at Mount Sinai and Duke-NUS Medical School have developed a rapid test to assess a person’s level of immunity to SARS-CoV-2 infection and subsequent COVID-19. The researchers refined a quantitative (q)PCR assay to assess levels of SARS-CoV-2-specific T cell activation from a blood…
Published on May 11, 2022
Immunotherapy unleashes the immune system to fight cancer, but it doesn’t work for all patients, and newly reported research may help to explain why. The study, headed by a team at Weill Cornell Medicine, indicates that the genetic program of T lymphocyte immune cells infiltrating malignant tumors, and the developmental…
Published on April 27, 2022
The COVID-19 pandemic has driven RNA into the public eye and there is increasing recognition of its importance in medicine. The intense scientific drive and the success of mRNA vaccines during the last two years has also benefitted biotech overall, with an increasing list of new RNA startups entering the…
Published on April 13, 2022
Harnessing the body’s own ability to seek and destroy cancer cells has been one of the most promising methods of treating cancer of the blood, like leukemia. The technology reprograms a type of immune cells, called T-cells, and then puts them back into the patient where they can do their…
Published on April 8, 2022
The terms minimal residual disease, measurable residual disease, and molecular residual disease, interchangeably referred to as MRD, denote what is left after cancer treatment with curative intent. Originally used to monitor patients with hematologic malignancies, MRD is becoming increasingly important in the field of solid tumor oncology because of its…
Published on March 24, 2022
Scientists have created an experimental immunotherapy that can shrink cancerous pancreatic tumors in a mouse model by exploiting pre-existing immunity conferred by tetanus vaccines and rendering the tumors vulnerable to the immune system. Pancreatic cancer is one of the most challenging cancers to treat. Patients with pancreatic tumors have dismal…