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Published on August 24, 2016
The global biochip market, driven by high demand from proteomic and genomic applications, along with growing adoption of personalized medicine, is expected to reach $25.8 billion by 2024 according to new research published by consulting firm Grand View Research. According to the report, other factors affecting the growth of the…
Published on August 5, 2016
To highlight its new Twins Study—and to coincide with National Twins Day—NASA’s Human Research Program (HRP) is releasing a new video entitled “Omics: Advancing Personalized Medicine from Space to Earth.” This is the final video in a series of eight which explores space through you by using omics to look…
Published on June 29, 2016
A team of investigators led by researchers at the University of Toronto has identified a set of prostate cancer biomarkers for use with non-invasive liquid biopsies for the identification of aggressive tumors before surgery. This new study—“Targeted proteomics identifies liquid-biopsy signatures for extracapsular prostate cancer”—published recently in Nature Communications advances…
Published on June 13, 2016
Researchers and physicians are increasingly learning that medical interventions can be more successful when they are tailored to the particular profile of the individual patient. Yet, defining that profile has proven tough, as it involves information on an individual’s genome, proteins, fats, and variety of other biomolecules that constitute the …
Published on May 16, 2016
We may soon hear cancer researchers say, “That’ll do pig, that’ll do.” To date, cancer researchers have contented themselves with using rodents in the laboratory, in part because of the additional costs of maintaining animals so large and as long-lived as pigs. Yet, with access to the tools of precision…
Published on March 29, 2016
A team of investigators at Beth Israel Deaconess Medical Center (BIDMC) recently published data that identified and validated an accurate 5-gene classifier for discriminating early pancreatic cancer from nonmalignant tissue—a finding that is a promising advance for the fourth leading cause of cancer death in the United States. “Pancreatic cancer…
Published on March 17, 2016
Expect the number of dementia patients to triple by 2050, but don’t expect any cures, not anytime soon. In hopes of learning how to slow dementia, scientists are trying to understand how the condition progresses at the molecular level, where drugs might be effective. For example, scientists based at Nanyang…
Published on February 1, 2016
Because sepsis is characterized by nonspecific symptoms and can progress quickly—with fatal results—biomarkers that can characterize the condition are dearly needed. Ultimately, multiple biomarkers may serve to characterize different aspects of the disease. With an eye toward this multibiomarker possibility, researchers at Lund University and the University of Zurich have…
Published on October 22, 2014
Many scientists point out that it’s become clear there are no simple universal strategies for the comprehensive analysis of complex proteomes. Although the application of omics technologies to biological samples generates hundreds to thousands of biomarker candidates, a small number actually make it through the pipeline to clinical use, largely…
Published on October 10, 2014
Precision cancer therapy firm Perthera is partnering with the Robert H. Lurie Comprehensive Cancer Center of Northwestern University and the Northwestern Medicine Developmental Therapeutics Institute (NMDTI) to conduct a translational research program aimed at assessing the utility of integrating next-generation sequencing, proteomic, and phospho-proteomic data in oncology developmental therapeutics and…
Published on September 24, 2014
Clinical applications for mass spectrometry technology have exploded in recent years. Mass spectrometry analysis is often faster, cheaper, and more sensitive than other methods and is thus ideally suited for both diagnostics and therapeutic monitoring. “Mass spectrometry is finally being accepted by microbiologists as a powerful analytical tool and is…
Published on June 12, 2014
Technological advances such as high-throughput sequencing are transforming medicine from symptom-based diagnosis and treatment to personalized medicine as scientists employ novel rapid genomic methodologies to gain a broader comprehension of disease and disease progression. As next-generation sequencing becomes more rapid, researchers are turning toward large-scale pan-omics, the collective use of…
Published on June 12, 2014
Clinical proteomics applications rely on the translation of targeted protein quantitation technologies and methods to develop robust assays that can guide diagnostic, prognostic, and therapeutic decision-making. The development of a clinical proteomics-based test begins with the discovery of disease-relevant biomarkers, followed by validation of those biomarkers. “In common practice, the…
Published on May 28, 2014
The history of science is replete with instances of multiple discovery—the more or less simultaneous announcement of essentially the same breakthrough by independent researchers. Still, it may still seem uncanny that two separate research groups not only produced a draft map of the human proteome, they also published their results…
Published on April 15, 2014
Vural Özdemir, M.D., Ph.D., is editor-in-chief of OMICS: A Journal of Integrative Biology, published by Mary Ann Liebert, Inc. He is also an associate professor of human genetics at the council of higher education in Ankara, Turkey, and an independent scholar in science studies and advisor to the office of…