1980 Results
Sort By:
Published on May 16, 2016
We may soon hear cancer researchers say, “That’ll do pig, that’ll do.” To date, cancer researchers have contented themselves with using rodents in the laboratory, in part because of the additional costs of maintaining animals so large and as long-lived as pigs. Yet, with access to the tools of precision…
Published on May 13, 2016
Gliomas are the most common malignant brain tumors in humans, constituting about 30% of all brain and central nervous system tumors and 80% of all malignant brain tumors. Gliomas are very severe human brain tumors that are rarely curable. Interestingly, these tumors are strikingly similar in dogs and humans. Moreover,…
Published on May 6, 2016
Complex neurological disorders, such as autism, schizophrenia, and bipolar disorder (BD) are the likely result of the influence of both common and rare susceptibility genes. While common variation has been widely studied over the past several years, rare variant elucidation has only recently become possible through the use next-generation sequencing…
Published on May 3, 2016
In time, the narrow, tortuous paths followed by pioneers become wider and straighter, whether the pioneers are looking to settle new land or bring new biomarkers to the clinic. In the case of biomarkers, we’re still at the stage where pioneers need to consult guides and outfitters or, in modern parlance,…
Published on May 2, 2016
During a panel discussion among scientists at the World Economic Forum in Davos, Switzerland, in January 2016, moderator U.S. Vice President Joe Biden asked for examples of obstacles researchers and clinicians face in the effort to cure cancer. While several topics emerged, the big issue was Big Data—more particularly, the…
Published on April 29, 2016
In a new study lead by scientists at the University of Minnesota and Nantes University Hospital in France, researchers showed that the bacteria in a patient’s gut might predict their risk for life-threatening blood infections following high-dose chemotherapy. Approximately 20,000 cancer patients receive high-dose chemotherapy each year in preparation for…
Published on April 25, 2016
Stephen Kingsmore, M.D., D.Sc., president and CEO of Rady Children’s Institute for Genomic Medicine at Rady Children’s Hospital-San Diego, now holds the official Guinness World Records® designation for the fastest genetic diagnosis, for the results that he and clinicians published just seven months ago. The feat is being recognized today at…
Published on April 22, 2016
Human Longevity Inc. (HLI) will sequence and analyze up to 500,000 DNA samples from patients in AstraZeneca clinical trials over 10 years in one of four genomics-focused initiatives announced today by the pharma giant and its global biologics R&D arm MedImmune. The value of the collaboration with HLI and other…
Published on April 19, 2016
Illumina saw its stock price fall nearly 24% this morning after reporting estimated first-quarter results in which the company acknowledged lower-than-projected revenues—a result blamed on underperforming sales for its sequencing instruments. Illumina reported estimated first-quarter revenues of approximately $572 million, up 6% from the $539 million reported for the year-ago…
Published on April 19, 2016
Scientists at the University of California San Diego School of Medicine and the Broad Institute say they have developed a new computer algorithm—REVEALER—to better characterize the functional context of genomic variations in cancer. The tool, described in a paper (“Characterizing Genomic Alterations in Cancer by Complementary Functional Associations”) published in…
Published on April 15, 2016
The past several years have seen some exciting results for cancer immunotherapy. However, there remains a fundamental lack of understanding of immune system recognition in various cancers. Many large-scale sequencing efforts have added to our collective knowledge base, but too many of these studies have been deficient in comprehensive epidemiological…
Published on April 15, 2016
Illumina is committing $100 million over 10 years to a new venture capital firm whose investment priorities will be in line with the company’s vision. Illumina said the new firm—to be called Illumina Ventures—will be managed independently of the sequencing giant. However, Illumina will be the majority limited partner in…
Published on April 14, 2016
In a new study from the Association for Molecular Pathology (AMP), a global, non-profit organization serving molecular diagnostic professionals, researchers described the results from a 2015 analysis of the costs and health economic impact of several Current Procedural Terminology (CPT) genomic sequencing procedures (GSPs). The findings from this study were…
Published on April 4, 2016
Understanding the molecular mechanisms that bring about aberrant protein glycosylation is critical to uncovering the pathways that contribute to overall tumor progression. Little is known about the molecular basis of altered protein glycosylation, which is often the hallmark of many human cancers including colorectal cancers (CRC). Now, a new study…
Published on April 1, 2016
A team of researchers led by scientists at the University of Washington (UW) has completed the sequence and assembly of the Western lowland gorilla, our closest evolutionary relative next to the chimpanzee—using new sequencing technology based on longer sequence reads that allowed missing genes and missing forms of genetic variation…