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Published on December 9, 2022
A GWAS study of almost 3.4 million people with multiple ancestry has uncovered more than 3,800 genetic variants potentially associated with smoking and alcohol use. The subjects had African, American, East Asian, and European ancestry. The study appeared in Nature this week and was led by Scott Vrieze, Department of…
Published on October 14, 2022
Tom Lawry, National Director for AI, Health & Life Sciences at Microsoft spent some time talking to editor in chief Damian Doherty about his new book Hacking Healthcare—How AI and the Intelligence Revolution will Reboot an Ailing System. Tom’s book shines light on how the pandemic, despite its destructive force,…
Published on August 17, 2022
A new study suggests a new way for hematologic oncologists to protect older patients from the risks of medication interactions. As part of the Older Adult Hematologic Malignancies Program, investigators from Brigham and Women’s Hospital and the Dana-Farber Cancer Institute studied the association between older patients with blood cancers who were…
Published on May 25, 2022
A recent study of medical cannabis use found that for most oncology patients, pain measures improved significantly, other cancer-related symptoms also decreased, the consumption of painkillers was reduced, and the side effects were minimal. Published in Frontiers in Pain Research, these findings suggest that medicinal cannabis can be an alternative to…
Published on March 23, 2022
A collaborative Canadian study has discovered sex-specific mechanisms of chronic pain processing in neurons of the spinal cord that are conserved across species from rodents to humans, a finding which could lead to the development of more personalized therapies for this indication in the future. Only recently have pain scientists…
Published on February 16, 2022
Larisa Cavallari,University of FloridaCollege of Pharmacy When University of Florida (UF) Health started recommending genotyping to guide clopidogrel prescribing about ten years ago it was a “life or death issue,” explains Larisa Cavallari, professor of Pharmacotherapy and Translational Research at UF. The drug is administered after…
Published on January 14, 2022
Australian cell therapy biotech Mesoblast has released results this week showing its allogenic cell therapy, designed to target pain in those with degenerative disc disease, provides pain relief for at least three years. The last year has been mixed for the company, which saw shares crash by 21% in December…
Published on December 1, 2021
Growing evidence that precision medicine would save lives is what prompted each of the health systems covered in this article to adopt an aggressive program early. “This means improving care for our patients,” says Konstantinos N. Lazaridis, M.D., of Mayo Clinic. “It gives us more specific information about what causes…
Published on October 27, 2021
Researchers at Duke University Medical Center, and colleagues at the University of California (UC), Irvine, have now trawled through a “junkyard of cancer drugs” to identify a compound, kenpaullone (KP), that might be repurposed as a powerful pain medication. Studies indicated that kenpaullone acts by boosting levels of an ion…
Published on June 15, 2020
Molecular diagnostics for everything from cancer testing to what medications doctors should prescribe—or not prescribe—for heart disease, mental health and a host of other conditions have been steadily increasing their share of the diagnostics pie over the past five years. That was until COVID-19 and the subsequent, ongoing global pandemic…
Published on March 24, 2020
Data-based medicine might sound like a better way to treat patients. The advances in collecting information, especially sequencing genes, promise to push physicians closer to improved patient care. Even more, the combination of information on a patient’s genes (genotype) and traits (phenotype) could be combined to make smarter decisions on…
Published on February 13, 2020
Biomarkers are indicators of biological events. They are either present, or not; they may increase or decrease; or simply change form. They relate to normal biological states, the presence of disease (or the risk of it), or in response to intrusions into the body, including medical treatment or injury. Above…
Published on September 30, 2019
Edward Abrahams, Ph.D., has been president of the Personalized Medicine Coalition (PMC) since its founding in late 2004. After serving as an anchor partner for the Annual Personalized Medicine Conference in collaboration with Harvard Medical School from 2005 to 2015, PMC took over the programming and management of the conference…
Published on June 6, 2019
The NIH plans to spend $42 million over five years to fund clinical trials designed to evaluate whether and how the management of diseases such as high blood pressure, depression and chronic pain can be improved through genomic medicine. The trials to be funded constitute the second phase of the…
Published on August 2, 2018
The Foundation for the National Institutes of Health (FNIH) Biomarkers Consortium (BC) has launched a project designed to seek regulatory qualification of new biomarkers that predict the change in joint damage over time from osteoarthritis (OA) in the knee. The PROGRESS OA: Clinical Evaluation and Qualification of Osteoarthritis Biomarkers project,…