326 Results
Sort By:
Published on November 9, 2017
Non-profit precision medicine organization CureOne has announced a cancer research collaboration with the Washington University School of Medicine in St. Louis that will leverage the school’s next-generation sequencing (NGS) laboratory and genomics and pathology services (GPS) to help the continued development of the N1 Registry. The N1 Registry is a…
Published on November 1, 2017
Scientists at the Albert Einstein College of Medicine in New York recently published research that offers new insights into the role microbiome composition and enzyme activity plays on the likelihood cancer patient will suffer from potentially life-threatening diarrhea following treatment with the chemotherapy agent irinotecan. The research indicates it may…
Published on October 12, 2017
Four institutions have been awarded $53.6 million in funding over five years by the NIH’s National Cancer Institute (NCI) toward a national effort to expand the reach of cancer immunotherapy to benefit more patients. The NCI has awarded cooperative agreements to support four Cancer Immune Monitoring and Analysis Centers (CIMACs)…
Published on September 12, 2017
Researchers have constructed the first-ever predictive model of inflammatory bowel disease (IBD), revealing the complexity of its immune network through a multi-omics approach—a complexity that they hope will yield potential targets for new treatments. The model consists of individual networks constructed using molecular data generated from intestinal tissue samples isolated…
Published on August 31, 2017
Protein folding is a fundamental function in the mundane operations of a cell’s daily life. Yet, when this task goes wrong, it becomes readily apparent how vital of a role 3D structure plays for the vast majority of protein molecules. In the past, scientists concluded that the aberrantly assembled proteins…
Published on July 21, 2017
Boehringer Ingelheim will apply Philogen’s proprietary Encoded Self-Assembling Chemical (ESAC) library technology platform to discover and optimize novel small-molecule–based therapeutics, through a collaboration whose value was not disclosed. ESAC enables Philogen to construct and screen DNA-encoded chemical libraries that according to the company are of unprecedented size and quality. Philogen…
Published on May 23, 2017
Seattle Children’s said today it has launched the first clinical trial designed to better understand how the immune system drives both inflammatory bowel disease (IBD) in pediatric autoimmunity patients and graft-versus host disease (GVHD) in pediatric bone marrow transplant patients. The PREDICT (Precision Diagnostics in Inflammatory Bowel Disease, Cellular Therapy…
Published on April 28, 2017
Cambridge Epigenetix said today it has strengthened its position in epigenetic biomarker discovery by licensing technologies from Boston Children’s Hospital that the company said could improve the diagnosis and treatment of cancer and other diseases. Through an exclusive license agreement whose value was not disclosed, Cambridge Epigenetix said it has…
Published on April 18, 2017
More than a year after CMS first began warning diagnostic company Theranos of what it deemed to be deficient laboratory practices, the two entitites have reached a legal agreement that will see Theranos pay a $30,000 fine and will be barred from operating a clinical laboratory for two years. The…
Published on February 3, 2017
The National Cancer Institute (NCI) recently completed a material transfer agreement with German autoantibody screening and diagnostic developer Protagen AG, for the use of Protagen’s SeroTag immune system profile technology. The collaboration will be led by Jeffrey Schlom, Ph.D., chief of the laboratory of tumor Immunology and biology at the…
Published on January 18, 2017
Johns Hopkins researchers have published new data that suggests epigenetic changes controlling how DNA operates, provides survival advantages to a subset of pancreatic cancer cells. The results, published in the Nature Genetics article, “Epigenomic Reprogramming during Pancreatic Cancer Progression Links Anabolic Glucose Metabolism to Distant Metastasis,” show that these changes…
Published on January 9, 2017
Global pharma AbbVie, genomics data company WuXi NextCODE, and life science startup company Genomics Medicine Ireland Ltd. (GMI) have entered a 15-year strategic alliance focused on population genomics research in Ireland that will focus on major chronic diseases within oncology, neuroscience and immunology. The goal of the alliance is to…
Published on October 28, 2016
Investigators at the University of Colorado (CU) Cancer Center came across unexpected findings recently, while trying to detect genomic rearrangements in cancer genomes while utilizing their mouse model of B cell lymphoma. To their surprise, the Colorado researchers found more than 1,000 genetic translocations in their mouse model, a result…
Published on October 26, 2016
An international team of researchers led scientists at Mainz University Medical Center in Germany has addressed the issue of different analysis software packages for mass spectrometry producing different results from the same raw data. The new study—published recently in Nature Biotechnology under an article entitled “A multicenter study benchmarks software…
Published on August 4, 2016
Researchers from the Johns Hopkins University School of Medicine have identified that gene expression profiling may assist in determining renal cell carcinoma patients who are unlikely to benefit from the anti-PD-L1 checkpoint inhibitor immunotherapy drug nivolumab (Opdivo). The recent study—“The Intratumoral Balance between Metabolic and Immunologic Gene Expression Is Associated…