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Published on July 19, 2016
Researchers at the Sanford-Burnham Prebys Medical Discovery Institute (SBP) have uncovered more than 100 new genetic regions that affect the immune response to cancer. The recent findings—“Mutation drivers of immunological responses to cancer”—published in Cancer Immunology Research, could assist scientists in the development of future treatments that enhance the immune…
Published on June 22, 2016
Adding to the ever expanding list of molecular diagnostic uses for next-generation sequencing, investigators at John Hopkins University report that they were able to diagnose or rule out suspected brain infections using the advanced genetic sequencing technique on brain tissue samples. The findings from this study, which were recently published…
Published on June 10, 2016
After the initial diagnosis of cancer, the next morbid news patients must deal with is the approximation of life expectancy and how well they can expect to respond to chemotherapeutic interventions. These estimates are historically based on precedents set by previous cancer patients. Yet, what if there were a way…
Published on May 24, 2016
An international team of researchers led by scientists at Uppsala University in Sweden presented their recently published findings at the annual conference of the European Society of Human Genetics yesterday. The new study found that men with blood cells that do not carry the Y chromosome are at greater risk…
Published on May 13, 2016
Gliomas are the most common malignant brain tumors in humans, constituting about 30% of all brain and central nervous system tumors and 80% of all malignant brain tumors. Gliomas are very severe human brain tumors that are rarely curable. Interestingly, these tumors are strikingly similar in dogs and humans. Moreover,…
Published on April 15, 2016
The past several years have seen some exciting results for cancer immunotherapy. However, there remains a fundamental lack of understanding of immune system recognition in various cancers. Many large-scale sequencing efforts have added to our collective knowledge base, but too many of these studies have been deficient in comprehensive epidemiological…
Published on January 4, 2016
Few other techniques in the laboratory so exquisitely blend the scientific fields of analytical chemistry, physics, and biology better than mass spectrometry (MS). Put simply, MS is designed to identify, and often quantify, the chemical makeup of a sample by measuring the mass-to-charge ratio of the ions that constitute that…
Published on September 8, 2015
Analyzing and compiling large datasets is one of the fundamental principles behind the development of computational systems that evolved into modern computers. But what happens when the datasets become so large or complex that traditional processing applications are inadequate? Such are the questions presented to Big Data scientists who are…
Published on March 13, 2015
Less than a month after winning its first FDA authorization, 23andMe is expanding beyond direct-to-consumer genetic testing by creating a new therapeutics group, and appointing Genentech’s recently retired evp of research and early development to lead the new unit. Richard Scheller, Ph.D., has been named 23andMe’s CSO and head of…