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Published on June 16, 2022
With evidence of the local community’s willingness to donate blood for research purposes to help alleviate the COVID-19 pandemic, San Diego Blood Bank and LunaPBC announced they will continue the collaboration by expanding these opportunities for blood donors to contribute to other health research efforts. The launch of the partnership…
Published on May 31, 2022
A Scandinavian study, led by the University of Bergen in Norway and including more than 4 million children, suggests that exposure to some anti-epileptic medications in the womb could increase children’s risk of developing neurodevelopmental disorders such as autism. The absolute risks for these conditions remained lower than five percent…
Published on May 23, 2022
Neuroscientists at Johns Hopkins University have pinpointed a mechanism in the brain of rats that causes a common type of age-related memory loss, which they hope will help improve understanding and treatment of conditions such as Alzheimer’s disease in humans. “We’re trying to understand normal memory and why a part…
Published on April 8, 2022
Narayanan “Bobby” Kasthuri Narayanan “Bobby” Kasthuri combines the power of electron microscopy and supercomputing to construct connectomes—comprehensive wiring diagrams of the neurons and synapses in the brain. In 2015, Kasthuri joined Argonne National Laboratory, becoming the first neuroscientist to be hired at the U.S. Department of…
Published on April 7, 2022
Researchers at the Broad Institute have identified rare protein-disrupting mutations in 10 genes that strongly increase an individual’s risk of developing schizophrenia. A second related study, a genome-wide association study (GWAS) brings to 287 the number of regions of the genome associated with schizophrenia risk. In what they call a…
Published on April 6, 2022
Fifteen “hotspots,” or loci, in the genome that either speed up brain aging or slow it down have been identified by researchers from a University of Southern California (USC)-led consortium. This finding could provide new drug targets for Alzheimer’s disease and other degenerative brain disorders, as well as developmental delays.…
Published on March 30, 2022
Research led by scientists at the University of Birmingham in the U.K. shows that higher expression of the inflammatory biomarker interleukin (IL)-6 can influence brain structure in regions of the brain linked to conditions such as autism spectrum disorder and schizophrenia. The results support earlier findings showing high levels of…
Published on March 21, 2022
The U.S. Food and Drug Administration (FDA) has approved Ztalmy (ganaxolone) for treatment of seizures associated with cyclin-dependent kinase-like 5 deficiency disorder (CDD), a rare form of genetic epilepsy, in patients two years of age and older. This is the first FDA-approved treatment specifically for CDD. The drug is a…
Published on March 15, 2022
The antimalarial drug hydroxychloroquine (HCQ) might boost the effectiveness of chemotherapy against some types of cancer by inhibiting pathways that drive drug resistance, suggest results from research led by the University of Pittsburgh. The newly reported work published in the Proceedings of the National Academy of Sciences (PNAS), found that among…
Published on February 10, 2022
An international team of scientists has used atlases of the human brain informed by genetics to identify hundreds of genomic loci. They found 440 genome-wide significant loci in the discovery cohort and 800 in a post-hoc combined meta-analysis. The work was led by Chi-Hua Chen, PhD, associate professor in the…
Published on February 8, 2022
Ovid Therapeutics has announced it will partner with U.K.-based artificial intelligence (AI) biotech Healx to develop and bring better treatments for Fragile X syndrome to the clinic. Ovid is based in New York and specializes in rare neurological disease treatments. It has several in the pipeline and has already had…
Published on January 28, 2022
Researchers at the University of California, San Francisco (UCSF), and colleagues have categorized all the cells that form the blood vessels of the human brain, along with their locations and the genes transcribed in each. The atlas characterizes more than 40 previously unknown cell types. The team suggests that their…
Published on January 26, 2022
Finland’s national public health project FinnGen, which aims to collect genomic data from 500,000 Finns—about 10% of the country’s population—announced that it has partnered with U.S.-based Metabolon to leverage metabolomics data to inform how the genetic influences within individuals manifest in biological function and the development of diseases. FinnGen was…
Published on January 13, 2022
A team based at Stanford University has broken previous world records by sequencing a whole human genome in just five hours and two min using Oxford Nanopore’s PromethION 48 sequencer. The record was achieved by Euan Ashley, a professor and clinician at Stanford University School of Medicine, and his team…
Published on December 21, 2021
Scientists at Northwestern Medicine looking to understand the link between children with autism and epilepsy have identified a critical brain protein that quiets overactive brain cells and is at abnormally low levels in children with autism. The findings, reported in the journal Neuron, noted the protein can be detected in…