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Published on June 30, 2020
Researchers at the University of California, Riverside (UCR) published a study “Interpersonal Gut Microbiome Variation Drives Susceptibility and Resistance to Cholera Infection” in Cell that describes how the gut microbiome helps people resist cholera, which can kill within hours if left untreated and sickens as many as four million people a year.…
Published on June 26, 2020
Clinical laboratories are showing signs of rallying after the recent slump in activity due to COVID-19, according to a new study from Arlington, Va.-based Kalorama Information, an in vitro diagnostics market research firm. The study, released June 25, found labs are running more tests and a greater variety of them…
Published on June 26, 2020
Researchers from an NIH-funded consortium are preparing to recruit nearly 2,600 participants whose data will be incorporated into maps of the molecular changes to the human body wrought by exercise—maps that may lead someday to greater use of personalized exercise regimens or exercise-mimetic drugs for people unable to exercise. The…
Published on June 24, 2020
The NIH’s National Heart, Lung, and Blood Institute (NHLBI) and the World Health Organization (WHO) have both halted clinical studies of hydroxychloroquine conducted as part of larger multi-drug trials based on efficacy, while Novartis ended its Phase III due to its inability to recruit enough patients. The clinical setbacks—announced Saturday…
Published on June 23, 2020
Invitae has agreed to acquire ArcherDx for up-to-approximately $1.4 billion, in a deal that would bring germline and somatic testing, liquid biopsy technologies and services, as well as tumor tissue genomic profiling onto a single platform The deal—announced just two weeks after ArcherDx filed for a $100 million initial public…
Published on June 19, 2020
The difference in the severity of COVID-19 from one patient to the next is a matter of intense research. Some hypotheses (none of which have been proven) focus on the amount of virus one initially comes into contact with, potential immunity from previous infections with similar coronaviruses, age and previous…
Published on June 18, 2020
Illumina announced yesterday it has acquired BlueBee, which provides a rapidly configurable data analysis platform for researchers and clinicians alike. Price of the acquisition was not disclosed. According to Illumina, BlueBee’s genomics analysis solutions which are designed to extract insights from genomic data into its cloud portfolio, will allow the…
Published on June 16, 2020
The FDA on Monday repealed the emergency use authorization (EUA) it granted in March to anti-malarial drugs chloroquine phosphate and its less toxic metabolite hydroxychloroquine sulfate as treatments for COVID-19. The agency citing a lack of consistent replication of earlier promising results and a randomized controlled clinical trial that showed…
Published on June 15, 2020
COVID-19 testing has been a failure in the United States since the very onset of the outbreak. Sick patients have had to wait for hours in lines outside hospitals or overnight in their cars. Those who were able to get their noses swabbed are subjected to a second wait for…
Published on June 15, 2020
While the clinical world has just begun to realize the promise of genomics to inform more precise care for individual patients, scientists also are pushing ahead with the development of clinical tools using other ’omics. The studies of proteins and metabolites—proteomics and metabolomics, respectively—offer considerable promise. In most cases, though,…
Published on June 15, 2020
As the field of precision medicine matures, it requires evermore technological improvements across a broader base of disciplines. Our list of half-a-dozen companies that are providing innovative solutions is no exception. From new applications of NGS and non-invasive testing, to leveraging technology to handle disparate datasets and solve genetic counseling…
Published on June 15, 2020
Molecular diagnostics for everything from cancer testing to what medications doctors should prescribe—or not prescribe—for heart disease, mental health and a host of other conditions have been steadily increasing their share of the diagnostics pie over the past five years. That was until COVID-19 and the subsequent, ongoing global pandemic…
Published on June 9, 2020
With more than 134,000 diagnosed cases of COVID-19 to date, California trails only New York and New Jersey of the most cases in the U.S. Now, small-scale investigation into the epidemiological origins of SARS-CoV-2 in northern California suggests that, distinct from virus transmission patterns identified elsewhere, the virus arrived in…
Published on June 3, 2020
Scientists at the UNC School of Medicine seeking to understand which cells in the respiratory tract are infected SARS-VoC-2, and how it gets into the lungs in the patients who develop pneumonia, has allowed them to characterize some of the ways it infects the nasal cavity and infects and replicates…
Published on June 2, 2020
Maintaining a balance between patient data-sharing and patient privacy has always been tricky. Laws and hospital policy require that any shared patient information should be protected from a variety of identifying information given the exquisitely personal nature of health data. Yet, that very same information represents a rich store of…