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Published on May 26, 2020
Patients with the skin cancer melanoma who have inherited a specific variant of the cholesterol carrying gene APOE, which is associated with increased risk for Alzheimer’s and other diseases, have increased survival compared with people who have inherited other variants of this gene. The research, which was published in the…
Published on May 21, 2020
Has Abbott announced a government contract to supply millions of its laboratory-based IgG antibody tests to National Health Service (NHS) laboratories across the U.K. over the coming months. Abbott has capacity to provide significant numbers of tests to the UK and has already shipped 800,000 antibody tests this week to…
Published on May 18, 2020
A collaboration between the labs of Alessandro Sette, Dr. Biol. Sci., professor in the Center for Infectious Disease and Vaccine Research, and Shane Crotty, PhD, professor at La Jolla Institute for Immunology, is starting to fill in the massive knowledge gap and is providing the first cellular immunology data from…
Published on May 15, 2020
Since the FDA approved the use of convalescent plasma therapy in COVID-19 in March, several clinical trials immediately put it to the test. Results of one of those trials from the Houston Methodist hospital system in severely/critically-ill patients found that 11 of 25 (44 percent) treated patients eventually improved to…
Published on May 13, 2020
Toronto-based functional genomics entity The DNA Company announced it bought for $30 million My Pain Sensei (MPS), a digital therapeutics pain management app that leverages artificial intelligence (AI), and via the acquisition has formed a new company named My Next Health. The acquired MPS platform—developed via an engagement with IBM—combines…
Published on May 7, 2020
CRISPR engineering biology company Sherlock Biosciences today announced today that it received Emergency Use Authorization (EUA) from the U.S. Food and Drug Administration (FDA) for its Sherlock CRISPR SARS-CoV-2 test kit for the detection of the virus that causes COVID-19. “While it has only been a little over a year…
Published on May 7, 2020
Vaccine trials for SARS-CoV-2 are underway in the United States with NYU Grossman School of Medicine and the University of Maryland as the first centers to enroll patients. The randomized Phase I/II clinical trial will seek to enroll healthy patients to receive either one or two doses of one of…
Published on May 6, 2020
UK-based Iceni Diagnostics is developing a home-use SARS-CoV-2 diagnostic using glycan biology with the goal of having the test validated by autumn. Development of the hand-held device is being conducted at the University of East Anglia & John Innes Centre (JIC) spinout and supported by scientists at the Manchester Institute…
Published on May 5, 2020
An international team of researchers announced Monday that they have identified a fully human monoclonal antibody that prevents SARS-CoV-2 from infecting cultured cells. Discovery of the antibody, which also neutralizes the related SARS-CoV coronavirus, by scientists from Utrecht University, Erasmus Medical Center, and Harbour BioMed (HBM) represents an initial step…
Published on May 4, 2020
The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health announced today the launch of a study to help determine the rate of infection of the novel coronavirus in children and their families. The study, named Human Epidemiology and Response to SARS-CoV-2 (HEROS) has…
Published on April 27, 2020
Researchers are working around the clock, innovating ways to improve the COVID-19 testing process. Recently, a group of researchers from Yale University presented findings that suggest that one improvement could be made right at the beginning of the testing process—in the choice of the sample to be tested. Although the…
Published on April 24, 2020
Researchers headed by a team at the University of Illinois, Urbana-Champaign, have developed what they claim is an inexpensive, sensitive smartphone-based device that can detect viral and bacterial pathogens in about 30 minutes, and could be adapted to test for SARS-CoV-2. The platform comprises a cartridge-housed microfluidic chip that carries…
Published on April 23, 2020
A clinical trial for a coronavirus vaccine candidate developed by researchers at the University of Oxford will begin today in the U.K., the first trial of its kind in the country, said U.K. Health Secretary Matt Hancock in a recent press briefing. The U.K. government has pledged to support the…
Published on April 20, 2020
The unfortunate reality for most cancer patients is that they will face resistance to one or more chemotherapeutic agents prescribed to eliminate their disease. Even more problematic, once a patient’s tumor is resistant to one type of chemotherapy, it is much more likely to be resistant to other chemotherapies as…
Published on April 17, 2020
A new CRISPR-based antiviral strategy targeting the SARS-CoV-2 virus appears to effectively degrade RNA. The CRISPR-Cas13 approach called PAC-MAN (Prophylactic Antiviral CRISPR in huMAN cells) also proved effective against H1N1 human influenza A, another coronavirus, in human lung epithelial cells. With these findings, the researchers from Stanford University who developed…