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Published on March 21, 2017
Investigators at Purdue University Center for Cancer Research recently published data on a new liquid biopsy approach that identifies a series of proteins in blood plasma that, when elevated, signify that the patient has cancer. The new study, which was published recently in Proceedings of the National Academy of Sciences…
Published on March 7, 2017
HudsonAlpha Institute for Biotechnology said today it is launching a clinical program for adults interested in gaining insights into their health and their responses to specific medications base on their genomic profile. Insight Genome uses whole-genome sequencing to tell patients about their risks for developing specific medical conditions, or passing…
Published on February 13, 2017
RPRD (Right Person Right Drug) Diagnostics said today its diagnostic platform will be used by Children’s Minnesota in a collaboration designed to advance pharmacogenomic testing. Under the collaboration, the value of which was not disclosed, Children’s Minnesota will use RPRD’s platform within the pediatric health system’s cancer and blood disorder…
Published on February 2, 2017
Investigators from the Research Centre of Applied and Preventive Cardiovascular Medicine (CAPC) at the University of Turku, Finland, have studied over ten million DNA variations and recently found new links between the human genome and inflammation tracers. The new study—published recently in the American Journal of Human Genetics through an…
Published on January 31, 2017
Indivumed said today it will provide access to its quality tissue sample and clinical and molecular data collection methods to Regeneron Pharmaceuticals in order to support the drug developer’s cancer research programs. The value of the agreement was not disclosed. Under the terms of the agreement, Indivumed will provide Regeneron…
Published on January 16, 2017
A new study from investigators at 10x Genomics and the Fred Hutchinson Cancer Research Center demonstrated the ability of a newly developed single-cell RNA-sequencing (scRNA-seq) system that can be used to dissect transcriptomic heterogeneity from patients with acute myeloid leukemia (AML). Findings from the new study were published online today…
Published on January 13, 2017
Researchers at The University of Texas Health Science Center at Houston (UTHealth) have just developed a framework to understand how whole genome sequence (WGS) data can be analyzed to identify genetic variations that raise or lower risk of disease. The findings from this new study were published recently in the American…
Published on January 4, 2017
German clinical-stage biopharma company Affimed and MD Anderson today announced a development and commercialization agreement in immuno-oncology that will evaluate Affimed’s bispecific antibodies in combination with the natural killer cell (NK) technology of MD Anderson. Affimed’s calls its bispefic antibodies “TandAbs” due to their tandem antibody structure, which is designed…
Published on December 22, 2016
Regeneron Pharmaceuticals and Geisinger Health System today published in Science details of their DiscovEHR precision medicine collaboration that is leveraging large-scale sequencing and de-identified data from electronic health records to guide genomic medicine and genomics-guided therapeutic discoveries. Geisinger is a healthcare system that provides coverage to people in parts of…
Published on December 14, 2016
Circulating tumor DNA (ctDNA) diagnostics company Trovagene announced this week it will eliminate 20 jobs as it restructures its business to focus on selling its test kits and systems to research institutions, cancer centers, and clinical service facilities. The company’s announcement did not specify the percentage of workforce to be…
Published on November 10, 2016
Scientists at Stanford University School of Medicine have just described in a new study how sequencing minute bits of DNA circulating in the blood of lymphoma patients can accurately identify the cancer subtype and pinpoint mutations that might cause drug resistance. The findings from this new study were published recently…
Published on November 1, 2016
A team of investigators led by scientists at St. Jude Children's Research Hospital and the Washington University Pediatric Cancer Genome Project (PCGP) has published a comprehensive map of the genomic landscape for the form of acute myeloid leukemia (AML) called core-binding factor acute myeloid leukemia (CBF-AML). This new work reveals…
Published on October 11, 2016
A new study being conducted by Sanford Health is currently enrolling patients to determine how genomic profiling could help improve treatment options for patients with advanced, or rare forms of cancer. The Community Oncology use of Molecular Profiling to Personalize the Approach to Specialized cancer treatment at Sanford (COMPASS) trial,…
Published on October 3, 2016
Scientists at Johns Hopkins University believe they are closer to understanding the genetic mechanism of a rare, complex, multiple-gene disorder called Hirschsprung's disease. The results from the latest study—entitled “Enhancer Variants Synergistically Drive Dysfunction of a Gene Regulatory Network In Hirschsprung Disease” and published in Cell—suggest that many patients develop…
Published on September 9, 2016
Molecular diagnostics company Biocept announced today it will collaborate with Shilpa Gupta, Ph.D., of the University of Minnesota to observe the performance of the company’s liquid biopsy platform to detect the expression of PD-L1 and androgen receptor (AR) in patients diagnosed with bladder and prostate cancers. Biocept’s Target Selector™ platform…