An experimental form of immunotherapy that uses an individual’s own tumor-infiltrating lymphocytes (TILs) seems promising against metastatic breast cancer, according to results from an ongoing clinical trial led by researchers at the National Cancer Institute (NCI). This is a step forward for using adoptive cell therapy in solid tumors, one…

Pembrolizumab appears effective for aggressive endometrial (uterine) cancer, according to results from an international Phase II clinical trial led by researchers at The Ohio State University Comprehensive Cancer Center (OSUCCC). This immunotherapy is currently approved by the U.S. Food and Drug Administration (FDA) to treat several other forms of cancer.…

When his wife retrieved the Christmas lights from their garage in mid December, Foghorn Therapeutics President and CEO Adrian Gottschalk recalled, the decorations she unpacked presented an apt analogy for explaining the science behind his company, a developer of precision therapies. Just as the string of lights was tangled up…

Over the last week, the world of cancer research, diagnostics and therapeutics has been congregating on the European Society of Medical Oncology (ESMO) website to view a wide variety of cutting-edge research presentations at the organization’s annual conference. The biggest congress in Europe with a focus on cancer research, the…

A team of scientists, led by investigators at the Albert Einstein College of Medicine just published new findings suggesting that Gardnerella bacteria in the cervicovaginal microbiome may serve as a biomarker to identify women infected with human papillomavirus (HPV), who are at risk for progression to precancer. The findings—published recently in PLOS Pathogens through…

New advances in single cell RNA sequencing technology has brought researchers from the UK closer to discovering the cellular origin of a multitude of ovarian cancer subtypes, which they hope will eventually allow for the development a screening tool and better treatment options for this silent killer of women. Ovarian…

Scientists at Uppsala University and the Sahlgrenska Academy, University of Gothenburg say they have developed a blood test that may provide a more precise diagnostic for suspected ovarian cancer that would eliminate the need for exploratory surgery. This could lead to a reduction in unnecessary surgery and to earlier detection…

Federally-funded research, including advances in -omics technologies, is driving both development of new treatments and advances in public health, paced by a 26% drop in the cancer death rate, The American Association for Cancer Research (AACR) said in its annual Cancer Progress Report. However, AACR Cancer Progress Report 2018 also…

Lucid Diagnostics, a subsidiary of medical device company PAVmed recently signed a worldwide licensing deal with Case Western Reserve University for its EsoCheck technology, a DNA biomarker test that provides a highly accurate diagnosis for Barrett’s Esophagus, a disease that is often early indicator of esophageal cancer. Under the terms…

Researchers at Johns Hopkins Kimmel Cancer Center have developed a multianalyte blood-based test called CancerSEEK that identifies eight circulating protein biomarkers and a panel of mutations in 16 cancer genes that could eventually be used as an early screening tool for cancer. “This test represents the next step in changing…

Cancer Genetics said today it acquired Indian-based BioServe Biotechnologies for about $1.9 million, primarily in stock and other deferred payments, in a deal designed to help the buyer scale up its genetic analysis, bioinformatics, and manufacturing operations while capitalizing on clinical diagnostics and trial growth in India and the Asian…

A study led by University of Maryland researchers has identified genetic mutations associated with persistent human papillomavirus (HPV) infection that could help identify women at risk for cervical cancer. “We found certain genetic variants were associated with having high-risk HPV infections, while other variants and human leukocyte antigen (HLA) genes…

Changes in the diversity of human papillomavirus (HPV) types following vaccination may affect future cervical cancer screening programs, suggests data from a study of different vaccination strategies among communities in Finland. The study’s lead author, Ville Pimenoff, from the Karolinska Institutet in Stockholm and Oulu University in Finland, told Inside…

The current methods for diagnosing human papilloma virus are if a person has visible symptoms on their skin, or if a person have an abnormal cervical smear result. This may all change in the future, as researchers with the Margaret Cancer Center report in Clinical Cancer Research that they have…

Scientists at the University of California (UC) San Diego School of Medicine have harnessed the power of artificial intelligence to tackle a significant challenge in cancer research: predicting when tumors will develop resistance to chemotherapy. Their study, published in Cancer Discovery, introduces a machine learning algorithm that decodes the intricate…